Nọmba Rifampicin Cas: 13292-46-1 Molecular Formula: C43H58N4O12

Ngwaahịa

Nọmba Rifampicin Cas: 13292-46-1 Molecular Formula: C43H58N4O12

Nkọwa dị mkpirikpi:

Nọmba Cas:13292-46-1

Aha kemịkalụ:Rifampicin

Ụdị molekụla:
C43H58N4O12

Okwu:9,17,19,21-hexahydroxy-23-methoxy-2,4,12,1///;2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b) furan-1,11 (2-h)-dione,5,6;3-(((4-methyl-1-piperazinyl)imino)methyl)-rifamyci;3-((4-methyl-1-piperazinyl)iminomethyl ) rifamycinsv; 8- (((4-methyl-1-piperazinyl) imino) methyl) rifamycinsv; 8- (4-Methylpiperazinyliminomethyl) rifamycinSV; 8- (n- (4-methyl-1-piperazinyl) formidoyl) -rifomycins; RIFAMPIN "LEPETIT"


Nkọwa ngwaahịa

Mkpado ngwaahịa

Nkọwapụta ngwaahịa

Ebe Na-agbaze 183 Celsius
Njupụta 1.1782 (atụmatụ siri ike)
nchekwa okpomọkụ 2-8 Celsius C
solubility chloroform: soluble50mg/ml, doro anya
ngwa anya ọrụ N/A
Ọdịdị na-acha uhie uhie na-acha uhie uhie na-acha uhie uhie
Ịdị ọcha ≥99%

Nkọwa

Rifampicin bụ ihe nrụpụta semisynthetic nke rifamicin B, ọgwụ nje macrolactam na otu n'ime ọgwụ nje karịrị ise sitere na ngwakọta rifamicin A, B, C, D na E, nke a na-akpọ mgbagwoju rifamicin, nke actinomycetes Streptomyces mediteranei mepụtara ( nocardia mediteranei).E webatara ya na omume ahụike na 1968. Njikọ nke rifampicin na-amalite site na ngwọta mmiri nke rifamicin, nke n'okpuru ọnọdụ mmeghachi omume na-eme ka ọ bụrụ ihe ọhụrụ nke rifamicin S (32.7.4), na nhazi etiti nke rifamicin O (32.7. 3).Ibelata nhazi quinone nke ngwaahịa a na hydrogen site na iji palladium na carbon catalyst na-enye rifamicin SV (32.7.5).Ngwaahịa a na-enweta na-enweta aminomethylation site na ngwakọta nke formaldehyde na pyrrolidine, na-enye 3-pyrrolidinomethylrifamicin SV (32.7.6).Iji tetracetate lead oxidize ngwaahịa na-esi na ya pụta na enamine na hydrolysis na-esote ya na ngwọta mmiri nke ascorbic acid na-enye 3-formylrifamicin SV (32.7.7).Ime nke a na 1-amino-4-methylpiperazine na-enye rifampicin achọrọ (32.7.8).

ojiji na onunu ogwu

A na-eji Rifampin mee ihe dị ka ọgwụ nje.Ọ bụ ihe nrụpụta semisynthetic nke rifamycin B, ọgwụ nje macrocyclic nke ebu Streptomyces mediterranei mepụtara.A na-eji Rifampin agwọ ụkwara nta, brucellosis, Staphlococcus aureus, na ọrịa ndị ọzọ na-efe efe.

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