Nọmba Rifampicin Cas: 13292-46-1 Molecular Formula: C43H58N4O12
Ebe Na-agbaze | 183 Celsius |
Njupụta | 1.1782 (atụmatụ siri ike) |
nchekwa okpomọkụ | 2-8 Celsius C |
solubility | chloroform: soluble50mg/ml, doro anya |
ngwa anya ọrụ | N/A |
Ọdịdị | na-acha uhie uhie na-acha uhie uhie na-acha uhie uhie |
Ịdị ọcha | ≥99% |
Rifampicin bụ ihe nrụpụta semisynthetic nke rifamicin B, ọgwụ nje macrolactam na otu n'ime ọgwụ nje karịrị ise sitere na ngwakọta rifamicin A, B, C, D na E, nke a na-akpọ mgbagwoju rifamicin, nke actinomycetes Streptomyces mediteranei mepụtara ( nocardia mediteranei).E webatara ya na omume ahụike na 1968. Njikọ nke rifampicin na-amalite site na ngwọta mmiri nke rifamicin, nke n'okpuru ọnọdụ mmeghachi omume na-eme ka ọ bụrụ ihe ọhụrụ nke rifamicin S (32.7.4), na nhazi etiti nke rifamicin O (32.7. 3).Ibelata nhazi quinone nke ngwaahịa a na hydrogen site na iji palladium na carbon catalyst na-enye rifamicin SV (32.7.5).Ngwaahịa a na-enweta na-enweta aminomethylation site na ngwakọta nke formaldehyde na pyrrolidine, na-enye 3-pyrrolidinomethylrifamicin SV (32.7.6).Iji tetracetate lead oxidize ngwaahịa na-esi na ya pụta na enamine na hydrolysis na-esote ya na ngwọta mmiri nke ascorbic acid na-enye 3-formylrifamicin SV (32.7.7).Ime nke a na 1-amino-4-methylpiperazine na-enye rifampicin achọrọ (32.7.8).
A na-eji Rifampin mee ihe dị ka ọgwụ nje.Ọ bụ ihe nrụpụta semisynthetic nke rifamycin B, ọgwụ nje macrocyclic nke ebu Streptomyces mediterranei mepụtara.A na-eji Rifampin agwọ ụkwara nta, brucellosis, Staphlococcus aureus, na ọrịa ndị ọzọ na-efe efe.