Nọmba Glybenclamide Cas: 10238-21-8 Ụdị Molecular: C23H28ClN3O5S

Nkọwa dị mkpirikpi:

Nọmba cas: 10238-21-8

Aha kemịkal: Glybenclamide

Ụdị molekụla:C23H28ClN3O5S

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Nkọwa ngwaahịa

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Ụdị okwu

5-CHLORO-N-[2-[4-[[(CYCLOHEXYLAMINO)CARBONYL]AMINO]-SULFONYL]PHENYL]ETHYL]-2-METHOXYBENZAMIDE
5-CHLORO-N-[2-[4-[[(CYCLOHEXYLAMINO)CARBONYL]AMINO]SULPHONYL]PHENYL]ETHYL]-2-METHOXYBENZAMIDE
5-CHLORO-N-[4-(CYCLOHEXYLUREIDOSULFONYL)PHENETHYL]-2-METHOXYBENZAMIDE
GIBENCLAMIDE
GLIBENCLAMIDE
GLYBENCLAMIDE
GLYBENZCYCLAMIDE
GLYBURIDE
LABOTEST-BB LT00244861
MICRONASE
NP-[2-(5-CHLORO-2-METHOXYBENZAMIDO)ETHYL]BENZENESULFONYL-N'-CYCLOHEXYLUREA
1-( (p- (2- (Chloro-o-anisamido) ethyl) phenyl) sulfonyl) -3-cyclohexyl urea.
1-( (p-(2- (chloro-o-anisamido) ethyl) phenyl) sulfonyl) -3-cyclohexyl-ure
1-( (p-(2- (chloro-o-anisamido) ethyl) phenyl) sulfonyl) -3-cyclohexylurea
1- (p- (2- (5-Chloro-2-methoxybenzamido) ethyl) benzenesulfonyl) -3-cyclohexylurea
1-[[p-[2- (5-Chloro-o-anisamido) ethyl] phenyl] sulfonyl] -3-cyclohexylurea
1-[[p-[2- (chloro-o-anisamido) ethyl] phenyl] sulfonyl] -3-cyclohexyl-Urea
5-chloro-n-(2-- ((((cyclohexylamino)carbonyl)amino)sulfonyl) phenyl) ethyl) -2
Abbenclamide
adiab

Nkọwapụta ngwaahịa

Ebe Na-agbaze	173-175 Celsius C
Njupụta	1.1805 (atụmatụ siri ike)
nchekwa okpomọkụ	Ọnọdụ ikuku na-adịghị arụ ọrụ, Okpomọkụ ụlọ 2-8 Celsius
solubility	ethanol: soluble2mg/mL
ngwa anya ọrụ	N/A
Ọdịdị	White Crystalline ntụ ntụ
Ịdị ọcha	≥98%

Nkọwa

Glyburide (10238-21-8) bụ onye nnọchi anya hypoglycemic ọnụ nke ọgbọ nke abụọ.Ọrụ site na ATP-based K+ channel (Kir6, KATP) block.1?Na-egbochi mmiri iyi Kir6 na pancreas, na-eme ka mmụba nke intracellular Ca2+ na insulin secretion.Glyburide na-egbochikwa recombinant CFTR Cl- channels nwere IC50 nke 20 μM.2?cell permeable.