Nọmba Cas: 171599-83-0 Ụdị Molecular: C 2 2 H 3 0 N 6 O 4 S·C 6 H 8 O 7 = 666.70
| Ebe Na-agbaze | 49-53° |
| Njupụta | 1.05 g/cm³ |
| nchekwa okpomọkụ | ebe dị jụụ, kpọrọ nkụ ma zere ikpughe ọkụ ma ọ bụ okpomọkụ dị elu |
| solubility | na-agbaze ngwa ngwa na ethanol, acetone, ether, benzene na methylene chloride, mana ọ naghị esiri ya ike na mmiri. |
| ngwa anya ọrụ | [α]D20 = +61.0° (ihe ngwọta ethanol) |
| Ọdịdị | na-acha ọcha ka ìhè odo crystal ntụ ntụ |
N'oge mkpali mmekọahụ, akwara parasympathetic, non adrenergic na non cholinergic nerve (NANC) njedebe na sel endothelial vaskụla na-ahapụ nitric oxide (NO) n'okpuru ọrụ nke nitric oxide synthase (NOS).N'ime arịa ọbara, guanylate cyclase soluble (sGC) na-arụ ọrụ NO, na sGC na-arụ ọrụ na guanosin triphosphate iji mepụta cGMP.The cGMP na corpus cavernosum nke amụ na-arụ ọrụ vasodilator siri ike site n'ibelata mkpokọta Ca2 + na mkpụrụ ndụ anụ ahụ dị nro nke corpus cavernosum, na-eme ka izu ike nke mkpụrụ ndụ anụ ahụ dị nro na mmụba nke ọbara na-eruba n'ime corpus cavernosum, na-eduga. na erection.Jinyang alkali na-ebelata ogo nbibi nke cGMP, si otú a na-echekwa mmetụta ntụrụndụ nke cGMP na corpus cavernosum nke amụ ma na-ebute penile erection.Na vivo, cGMP wedara ma mekwaa ya site na PDE5.
Kwesịrị ekwesị maka ịgwọ ọrịa erectile dysfunction (ED) nke amụ, ọ dị irè maka arụrụ arụ erectile kpatara site na iji ọgwụ antidepressants, antipsychotics, na antihypertensive, yana maka arụrụ arụ erectile kpatara site na ịwa ahụ ma ọ bụ trauma.
Enwere ike ịme ya ka ọ bụrụ mbadamba nkume, mkpụrụ ọgwụ, capsules siri ike, capsules dị nro, enwere ike iji ya dị ka mmanya ọgwụ, mmiri mmiri ọnụ, kọfị, granules, mbadamba nkume a na-ata ahụhụ, lozenges, chịngọm, na ụdị usoro ọgwụgwọ ndị ọzọ.Maka ndị okenye, usoro ọgwụgwọ kwesịrị ịbụ 10-100mg kwa ụbọchị, nke nwere ike ịbawanye ma ọ bụ belata dịka ọnọdụ onye ọrụ si dị.Ọ ka mma ị were ya na afọ efu (karịsịa zere iji nri nwere oke abụba), aṅụla mmanya na-aba n'anya tupu ị na-aṅụ tii (ịṅụ mmanya ekwesịghị ịṅụ ya n'otu oge, nke a apụtaghị na ịṅụ mmanya na-aba n'anya n'otu oge). oge nwere ike ibelata ọrụ erectile nke Viagra).
Oge dị irè: Ọtụtụ ndị mmadụ na-ewere ya otu awa iji rụọ ọrụ.A na-atụ aro ka ị ṅụọ ọgwụ ihe dị ka otu awa tupu enwe mmekọahụ, na mmetụta ya na-adịru awa 48 ruo 72, ụfọdụ nwere ike ịdịru awa 116.
